Cardiovascular system : essential hypertension ,cerebrovascular disease , migraine , coronary disease

Respiratory disorders : hay fever, asthma , allergy, vasomotor rhinitis

Disorders of muscles and joints :fibrosis, rheumatoid arthritis

Gastro intestinal disorders : peptic ulcer , diarrhea , irregular bowel movements.

Endocrime disorders : hyperthyroidism, diabetes mellitus

Disorders in reproductive system : pre menstrual tension , menopausal changes

The anxieties and fears are lower the body resistance , making the individual vulnerable to various diseases .this is due to stress interferes with the immune system by reducing the overall number of lymphocyte. The wbc or lymphocyte are the cells which attack the foreign bodes such as disease causing bacteria , virus , fungi etc. by the experiments we proved that the frightened animal’s immune system not work properly and reduce the number of lymphocyte level during fear.